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Brecka repeatedly emphasizes that it should be approached carefully and ideally under medical guidance

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Following intravaginal administration of radiolabeled clotrimazole in patients with normal or inflamed vaginal mucosa, peak serum concentrations of clotrimazole 24 hours after insertion of a single 100 mg tablet of the drug are 0.03 ug/ml and peak serum concentrations 24 hours after administration of a cream containing 50 mg of the drug are 0.01 ug/ml

After extensive data processing, the 2D class averages exhibiting dimeric features were subjected to non-uniform refinement, resulting in a reconstruction of 3.7 resolution from 274,513 particles